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Journal of Nutrition Vol. 56 No. 1 May 1955, pp. 107-113
Copyright © 1955 by American Society for Nutrition
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Blood Ergothioneine and Dietary Oats1

Robert C. Baldridge

Department of Biological Chemistry, Medical School, University of Michigan, Ann Arbor, and the Department of Physiological Chemistry, Temple University School of Medicine, Philadelphia, Pennsylvania

1. Ergothioneine appears in the erythrocytes of the rabbit and the white rat following ingestion of oats. The blood level of the rat is related to the percentage of oats in the diet. The compound was not detected in the blood of rats fed purified (casein) diets or such diets supplemented with cabbage.
2. Administration of vitamin B12 has no effect on blood ergothioneine levels in the white rat.
3. Elevated blood levels of ergothioneine are not related to thyroid function as revealed by histologic examination and relative weight of rat thyroid tissue.


1 A report of this work was presented at the meeting of the Federation of American Societies for Experimental Biology, Atlantic City, April, 1954 (Baldridge, '54).

Manuscript received 2 December 1954.





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