QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by House, W. B. Articles by Hogan, A. G. Search for Related Content PubMed PubMed Citation Articles by House, W. B. Articles by Hogan, A. G.

Injury to Guinea Pigs That Follows a High Intake of Phosphates

The Modifying Effect of Magnesium and Potassium¹

Department of Agricultural Shemistry, College of Agriculture, University of Missouri, Columbia

Our earlier report that the consumption of an excess of phosphates is injurious to guinea pigs, was confirmed. The symptoms are slow gains in weight, the development of stiff joints, of calcium phosphate deposits, and a high mortality rate.

The symptoms were most severe on the rations that contained calcium 0.9%, phosphorus 1.7%, magnesium 0.04%, and potassium 0.41%.

When the rations were changed to contain approximately 0.35% of magnesium and 1.5% of potassium the damage to the animals was reduced remarkably. The animals made moderate gains in weight, few of them became stiff, deposits of calcium phosphate were rare, and the mortality rate was low.

Contribution from the Missouri Agricultural Experiment Station, Journal series No. 1467.

² Taken from a thesis to be presented by W. B. House to the Graduate School of the University of Missouri.

Manuscript received 25 September 1954.