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Journal of Nutrition Vol. 55 No. 2 February 1955, pp. 225-234
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Manganese Deficiency in the Duck1

Robert Van Reen and Paul B. Pearson

McCollum-Pratt Institute, The Johns Hopkins University, Baltimore, Maryland

1. The effects of a dietary deficiency of manganese were investigated using ducklings as the experimental subjects.
2. Forty milligrams of manganese per kilogram of diet are adequate for normal growth and prevention of perosis.
3. Alkaline phosphatase activity of liver, kidney, heart and plasma was reduced during the deficiency.
4. The decreased enzyme activity could not be correlated with the presence of an inhibitor or an altered pH optimum of alkaline phosphatase.

1 Contribution no. 91 of the McCollum-Pratt Institute. This work was supported (in part) by the Medical Research and Development Board, Office of the Surgeon General, Department of the Army, Contract no. DA-49-007-MD-345.

Manuscript received 19 August 1954.




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