QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Dickson, W. M. Articles by McGinnis, J. Search for Related Content PubMed PubMed Citation Articles by Dickson, W. M. Articles by McGinnis, J.

The Effect of Terramycin or Fish Solubles, or Both, on the Growth, Adrenal Glands and Gonads of the Rat

Department of Veterinary Physiology and Pharmacology and Department of Poultry Science, The State College of Washington, Pullman

1. Fish solubles gave a significant (P < 0.05) growth response at 21 days post weaning with a practical-type basal diet. With a semi-purified basal diet, fish solubles gave a very significant growth response at 21 and 49 days but not at 77 days post weaning. This growth response was measured by weight gains and by the increase in tail length.

2. Terramycin failed to stimulate growth of the normal healthy rat to a significant degree. In an experiment in which surgery (castration or sham-castration) was performed 14 to 20 days following weaning, significant (P < 0.05) growth stimulation was obtained after 49 days on the experimental diet. It is suggested that terramycin acted as a growth stimulant only to the animal subjected to stress.

3. There was some indication that both terramycin and fish solubles caused an increase in the weight of the adrenal gland in the growing rat.

4. Neither supplement affected the weight of the male sex organs of the growing rat.

5. The addition of fish solubles to a semi-purified basal diet caused a significant (P < 0.05) increase in the weight of the ovaries and uterus of the growing rat at 49 days post weaning. After 77 days on the experimental diets, fish solubles caused an increase (P < 0.1) in the weight of the uterus of intact females, but not in castrate females.

Manuscript received 2 July 1954.