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Dental Caries in the Albino Rat on High Sucrose Diets Containing Different Amounts of Aluminum

Department of Physiology, Division of Basic Sciences in the Health Services, Emory University, Emory University, Georgia

These experiments were undertaken to determine whether aluminum, like fluoride, when added to the diet in small amounts may offer some protection against dental caries.

No significant differences were found in the number of carious molars or in the caries scores as a result of the addition of aluminum in the amounts used in this study, either in non-desalivated or desalivated animals.

It may be concluded therefore that the difference in cariogenicity of two diets containing the same amount of sucrose but with different amounts of aluminum, as reported previously, is not due to the small amount of aluminum that was added to the salt mixture of one of these diets. The explanation of the lower cariogenicity of one of the high sucrose diets must be sought elsewhere.

The addition of aluminum up to 20 p.p.m. had no effect on appetite or growth of the animals.