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Journal of Nutrition Vol. 54 No. 1 September 1954, pp. 75-80
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The Effect of High Levels of Terramycin and Streptomycin on Longevity in the Rat1

C. E. French, J. A. Uram, R. H. Ingram and R. W. Swift

Department of Animal Nutrition, The Pennsylvania State University, State College

In an attempt to minimize the chronic pneumonia commonly observed in aged rats by the continual administration of streptomycin and terramycin incorporated in the diet at high levels (0.02 and 0.04%) beginning at the age of 11 months, the average life span of albino rats of both sexes was decreased about 10%.

Neither beneficial nor deleterious effects of the antibiotic supplementation were revealed by gross and histologic examination.

1 Authorized for publication on April 29, 1954 as paper no. 1874 in the Journal Series of the Pennsylvania Agricultural Experiment Station.

Manuscript received 10 May 1954.




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