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Journal of Nutrition Vol. 53 No. 4 August 1954, pp. 557-562
Copyright © 1954 by American Society for Nutrition
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Interrelationships of Pantothenic Acid and Methionine in Lymphocyte Production by Rats1

James S. Dinning, Ruth Neatrour and Paul L. Day

Department of Biochemistry, School of Medicine, University of Arkansas, Little Rock

Sprague-Dawley rats were fed diets with graded levels of methionine with and without pantothenic acid. The methionine requirement for growth, survival, and lymphocyte production was higher in the absence of dietary pantothenic acid than in the presence of this vitamin. The results indicate that pantothenic acid and methionine are interrelated in the nutrition of the rat.

1 Research paper No. 1002, Journal Series, University of Arkansas. This investigation was supported by research grant No. G-647 (C6), National Institutes of Health, Public Health Service.

Manuscript received 15 March 1954.




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