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Journal of Nutrition Vol. 53 No. 2 June 1954, pp. 259-263
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Failure of Vitamin B12 to Increase Survival of Progeny of Rats Fed an All-Plant Diet1

H. S. Perdue and Paul H. Phillips

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

The survival of the progeny of female rats which were fed an all-plant diet was not increased by the subcutaneous injection of 0.05 µg of vitamin B12 within 6 hours after parturition. An increase in the concentration of urea in their blood was not found except when their stomachs contained no milk. Starvation and dehydration were found to result in an increase in the concentration of urea in the blood of young rats from females which were fed either an all-plant diet or this diet supplemented with fish solubles.

1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. Supported in part by the Research Committee of the Graduate School from funds supplied by the Wisconsin Alumni Research Foundation.

Manuscript received 1 February 1954.




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