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Journal of Nutrition Vol. 53 No. 1 May 1954, pp. 83-91
Copyright © 1954 by American Society for Nutrition
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The Use of AA'-Dipyridyl for Determining the Amount of Ferrous Iron Formed in the Digestive Tract of Women Before and After the Addition of Beef to the Diet

Frances A. Johnston, Ruth L. Ingalls and Betty O. Muka

New York State College of Home Economics and the School of Nutrition, Cornell University, Ithaca

Two women consumed diets low in iron until the iron content of the feces reached a plateau. Then they were given 0.15 gm of {alpha}{alpha}'-dipyridyl orally on each of two days after which they continued on the low iron diet for two more days. The subjects repeated the same procedure with beef substituted for a part of the sugar in the diet. On neither diet did the iron content of the feces rise upon the administration of {alpha}{alpha}'-dipyridyl. This indicated that {alpha}{alpha}'-dipyridyl does not combine with ferrous iron in the digestive tract to form an insoluble compound and cannot be used to measure the amount of ferrous iron formed.

One subject absorbed very little and the other about one-third of the iron of beef.


Manuscript received 9 November 1953.





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