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Dental Caries in the Cotton Rat

XIV. Further Studies of Caries Production by Natural Diets with Especial Reference to the Role of Minerals, Fat, and the Stage of Refinement of Cereals¹

One Figure

Department of Biochemistry, University of Wisconsin, Madison

Experiments have been conducted to study the effect of minerals, especially calcium and basic mineral m xtures, fat, tooth maturity and the stage of refinement of cereals on the cariogenicity of natural diets fed to cotton rats.

Calcium carbonate, disodium phosphate, basic salt mixtures with and without calcium and near neutral salt mixtures containing calcium retarded the development of caries in the erupted tooth.

A low-mineral natural diet which produced extensive tooth decay when fed to weanlings was relatively non-cariogenic if fed to older animals. Oily fats were found to give partial protection against tooth decay when substituted for the "natural" fat of a cereal-milk diet.

Unsteamed oat groats were found to be more cariogenic than whole oats. The increased cariogenicity of processed oats occurred at the de-hulling step.

Manuscript received 4 August 1953.