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Journal of Nutrition Vol. 53 No. 1 May 1954, pp. 129-138
Copyright © 1954 by American Society for Nutrition
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The Effects of Vitamin B12, Organ Extracts, Yeast and Antibiotics on Emetine Toxicity in Rats

K. Guggenheim and S. Halevy

Laboratory of Nutrition, Department of Biochemistry, The Hebrew University-Hadassah Medical School, Jerusalem Israel

1. Vitamin B12, partially hydrolyzed extracts of liver, muscle, heart and kidney, aureomycin and streptomycin were found to increase the tolerance to emetine in protein-depleted rats, whereas yeast was without any effect.
2. The organ extracts exerted their protective action even in rats fed a full diet.
3. The protective effect of liver extract in protein depleted rats cannot be ascribed to its content of essential amino acids.

Manuscript received 18 January 1954.




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