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Department of Physiology, Emory University School of Dentistry, Emory University, Georgia, and Research Laboratories, Harvard School of Dental Medicine, Boston, Massachusetts
Litter mates of both albino rats and cotton rats were fed two synthetic diets that differed quantitatively in a considerable number of their constituents but were identical in their sugar content. One of these diets proved to be much more cariogenic than the other, indicating that the sugar content of the diet does not necessarily provide a measure of its cariogenicity.