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Journal of Nutrition Vol. 48 No. 2 October 1952, pp. 193-199
Copyright © 1952 by American Society for Nutrition
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Diminished Urinary Creatinine in Vitamin E Deficient Rats1

E. L. Hove and J. O. Hardin2

Department of Animal Husbandry and Nutrition, Agricultural Experiment Station of the Alabama Polytechnic Institute, Auburn

Rats on diets deficient in vitamin E excreted less creatinine than did control rats receiving this factor. The diminished creatinine excretion correlated significantly with the increased creatine excretion of the deficient animals.

On the 10% casein diet, without vitamin E, rats developed the low creatinine-high creatine pattern much sooner than rats on the 18% casein diet.


1 Published with the approval of the director of the Alabama Agricultural Experiment Station. Partly supported under Contract N9 onr 92100 with the Office of Naval Research. Thanks are expressed to Merck and Company for donation of vitamins used.

2 Present address: Ralston-Purina Laboratories, St. Louis, Mo.

Manuscript received 24 March 1952.





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