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Journal of Nutrition Vol. 47 No. 3 July 1952, pp. 375-382
Copyright © 1952 by American Society for Nutrition
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A Study of Lysine Deficiency and Nitrogen Balance under Ad Libitum and Force-Feeding Conditions1

One Figure

James W. Bothwell and J. N. Williams, Jr.

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

The effects of a lysine deficiency upon weight changes, nitrogen intake and nitrogen balance have been investigated, employing both ad libitum and force-feeding procedures.

A marked correlation between nitrogen intake and nitrogen balance was noted for all groups except the lysine-deficient force-fed group. During the first few days of force feeding the latter group showed a marked increase in nitrogen output which decreased as the animals evidenced marked deficiency symptoms.

1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. Supported in part by a grant from the Office of Naval Research, Department of the Navy, Washington, D. C.

Manuscript received 29 February 1952.




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