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Cariogenicity of Sugar-Containing Diets¹

Department of Physiology, Emory University Dental School, Emory University, Georgia

The number and extent of carious lesions in the teeth of albino rats of the Wistar strain on a high protein and a high fat diet containing 22% to 24% sugar were extremely small and of the same order of magnitude as in animals fed an ordinary stock diet. Increasing the sugar content of the diet so that it constituted 64% of the food mixture resulted in some increase in the carious damage to the teeth. The actual number and the actual extent of the lesions, however, were relatively small. Exposure of the animals to the possible systemic influence of a high sucrose diet in prenatal life did not increase the incidence of dental caries.

Manuscript received 9 November 1951.

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