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Effect of Vitamin B₁₂ and Folic Acid on Growth and Uricemia of Chickens Fed High Levels of Glycine^1,2,

Bureau of Animal Industry, U. S. Department of Agriculture, Beltsville, Maryland

1. Addition of 3, 6, and 9% glycine to vitamin B₁₂-deficient diets caused a growth depression and increased mortality in growing chickens.

2. Both vitamin B₁₂ and folic acid function in counteracting this toxicity; however, B₁₂ is somewhat more effective.

3. Addition of 6 or 9% glycine to the diet increased blood uric acid levels. Folic acid tended to decrease these high levels of uric acid in the blood.

4. Vitamin B₁₂ tends to increase the level of uric acid in the blood of young chickens.

² Presented at the 32nd annual meeting of the American Institute of Nutrition, Cleveland, Ohio, May, 1951.

Manuscript received 4 October 1951.

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