Journal of Nutrition OpenSOurce Diets- www.ResearchDiets.com

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 46 No. 1 January 1952, pp. 99-108
Copyright © 1952 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sauberlich, H. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sauberlich, H. E.

Effect of Aureomycin and Penicillin upon the Vitamin Requirements of the Rat1

H. E. Sauberlich

Department of Animal Husbandry and Nutrition, Agricultural Experiment Station of the Alabama Polytechnic Institute, Auburn

1. Studies were made on the effect of aureomycin and penicillin upon the growth of weanling rats fed diets deficient in certain B vitamins.
2. The addition of penicillin to the diet (0.01%) caused a marked stimulation in the growth of rats fed diets free of or low in thiamine, pyridoxine, pantothenic acid and, to some extent, riboflavin. Aureomycin (0.01%) had a similar effect in the case of pantothenic acid and thiamine deficiencies. The effect of the antibiotics on thiamine and pyridoxine deficiencies was evident whether sucrose or dextrin was used in the diet. The inclusion of penicillin or aureomycin in the completely vitamin-supplemented basal diet had no effect upon the growth of the animals.
3. Similar results were obtained whether the Alabama Experiment Station strain or the Rockland strain of rats was used.

1 Published with the approval of the Director of the Alabama Agricultural Experiment Station. The study was supported in part by a grant from the Society of the Sigma Xi. The antibiotics used in this study were generously furnished by the Lederle Laboratories Division, American Cyanamid Company (aureomycin), Merck and Company, Inc. (penicillin), and Sharp and Dohme, Inc. (sulfamerazine). The folacin was also donated by the Lederle Laboratories and all other vitamins were supplied by Merck and Company, Inc.

Manuscript received 14 September 1951.


This article has been cited by other articles:


Home page
 Arch Intern MedHome page
L. WAYNE, J. J. WILL, B. I. FRIEDMAN, L. S. BECKER, and R. W. VILTER
Vitamin B6 in Internal Medicine
Arch Intern Med, January 1, 1958; 101(1): 143 - 155.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]