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Journal of Nutrition Vol. 45 No. 1 September 1951, pp. 153-160
Copyright © 1951 by American Society for Nutrition
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Effect of Diet on Maze Learning in Second-Generation Rats. Folic Acid Deficiency1

J. R. Whitley, B. L. O'Dell and A. G. Hogan

Department of Agricultural Chemistry, University of Missouri, Columbia

Rats born to dams fed a ration low in folic acid and reared to near maturity on the same ration showed inferior maze learning ability as compared to paired controls from the stock colony. Supplementation of the maternal diet with folic acid resulted in offspring which learned as readily as the control animals.

1 Contribution from the Department of Agricultural Chemistry, Missouri Agricultural Experiment Station, Journal Series No. 1254. This investigation was supported in part by a research grant from the National Institutes of Health, U. S. Public Health Service.

Manuscript received 16 April 1951.


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