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Transamination Reaction in Normal and B6-Deficient Hamsters1

Two Figures

Gregory Shwartzman and Helen Hift

Division of Bacteriology, Laboratories of the Mount Sinai Hospital, New York, N. Y.

The transamination rate of the heart muscle of B6-deficient hamsters was found to be 30 to 40% lower than that of control ad libitum-fed or pair-fed animals. The in vitro addition of pyridoxal alone, pyridoxal and ATP, and pyridoxal phosphate was without effect. Injections of desoxypyridoxine into experimental animals and the in vitro addition of the drug alone or together with ATP failed to produce any significant changes. Deficient hamsters exhibited succinoxidase activities comparable to those of control animals.

1 These studies were made possible by a grant from the Commonwealth Fund.

Manuscript received 5 December 1950.




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Copyright © 1951 by American Society for Nutrition