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Studies on the Iodine Requirements of White Rats during Growth, Pregnancy and Lactation¹

Department of Agricultural Chemistry and Animal Husbandry, Purdue Agricultural Experiment Station, West Lafayette, Indiana

With rats grown for three successive generations on diets containing 25 to 525 µg of iodine per kilogram, the minimum dietary level needed to prevent thyroid enlargement was found to lie between 100 and 225 µg per kilogram. The growth rates of rats fed the different levels of iodine did not differ significantly.

Lowering the iodine content of the diet of female rats to 25 µg per kilogram did not interfere with reproduction or lactation; however, the thyroids of the newborn from dams at this level had the appearance of embryonic glands.

Manuscript received 24 February 1951.