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Biological Value of an Enzymatic Digest of Bovine Plasma1

Anthony A. Albanese, Reginald A. Higgons, George E. MacDonald, William C. Felch, Betty Vestal and Loukia Stephanson

Nutritional Research Laboratory and Department of Medicine, St. Luke's Hospital, New York, N. Y.

It has been found that the nitrogen retention and weight gains of male infants maintained on a "synthetic" milk diet in which an enzymatic digest of bovine plasma3 constituted the principal source of protein were equal, if not superior, to those obtained on an evaporated milk formula fed at the same fluid, caloric distribution and nitrogen levels. The nutritional value of the hydrolysate was not improved by reinforcement with isoleucine and methionine. Tests of the digest given parenterally to adult males showed an average utilization of 86.3% of the infused nitrogen. The possibility that the nutritional value of N derived from sources which include peptides may be greater than that of an equivalent amount of N in the form of a mixture of free amino acids is discussed.


1 The work described in this report was supported by funds from the Office of Naval Research and Baxter Laboratories, Inc.

3 See footnote 2, page 281.

Manuscript received 9 January 1951.


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Arch Intern MedHome page
G. A. GOLDSMITH, W. G. UNGLAUB, and J. GIBBENS
RECENT ADVANCES IN NUTRITION AND METABOLISM: Review of the Literature, 1951
Arch Intern Med, October 1, 1952; 90(4): 513 - 561.
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