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The Nutrition of the Mouse

X. Studies on the Utilization of High and Moderately Low Protein Diets for Growth in Four Strains of Mice¹

Four Figures

Department of Biology, Brown University, Providence, Rhode Island

1. A wide range of protein efficiency ratios was observed when mice of 4 highly inbred strains were studied under identical conditions.

2. Mice of the C₃H and A strains grew considerably more rapidly on a diet containing 10% casein than did mice of the C₅₇ and I strains.

3. The growth rates of all 4 strains studied were reduced by feeding a 90% casein diet.

4. The addition of NaHCO₃ or the substitution of lactalbumin for casein gave improved growth.

5. Total weight gains of C₃H and A strain mice over a 30-day period following weaning were essentially the same whether the diet contained 10% or 30% casein.

6. Mice of the C₅₇ and I strains gained more weight on a 30% than on a 10% casein diet.

Vitamins of the B complex were obtained through the courtesy of Hoffmann-LaRoche, Inc. Folic acid was furnished by the Lederle Laboratories Division, American Cyanamid Company.

Manuscript received 20 October 1950.