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The Effect of Protein Deficiency and Other Dietary Factors on the X Zone of the Mouse Adrenal

Four Figures

Evelyn Howard and Richard S. Benua1

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland

1. A partially protein deficient diet caused a very marked suppression of the X zone of the mouse adrenal.
2. A 77% casein diet resulted in appreciable reduction of the X zone, indicating that the X zone is maximally developed at moderate levels of dietary protein.
3. Replacement of a part of the carbohydrate by a mixed fat was without any marked effect on the X zone.
4. The X zone was larger on a synthetic diet than on chow.


1 Present address: Mayo Foundation, Rochester, Minn.

Manuscript received 13 June 1950.





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Copyright © 1950 by American Society for Nutrition