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Determination of Basal Metabolism of the Albino Rat from the Insensible Loss of Weight

(From the Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor.)

1. The heat lost by vaporization of water and the heat production of the albino rat, in the basal state, have been determined under standard conditions of 18 to 24 hours without food or water and an environmental temperature of from 25 to 31° C.

2. The heat lost by vaporization of water averaged 23.81 per cent of the basal heat production of the albino rat, with a maximal variation of 13.3 per cent from the average, which held for normal, thin, and obese albino rats of both sexes.

3. Under these standard conditions, the respiratory quotient of the albino rat is about 0.72, and the water of vaporization is approximately 100 per cent of the insensible loss of weight. Insensible loss of weight per hour x 0.58 x 100/25 x 24 equals calories per 24 hours.

We wish to express our gratitude to Doctor L. H. Newburgh for his interest in this work, and for his many helpful criticisms and suggestions.