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Hypervitaminosis a in the Dog

Six Figures

Department of Pathology, Harvard Medical School, Division of Nutritional Research, The Children's Hospital, and the Laboratory of Surgical Research, Boston City Hospital, Boston, Massachusetts

1. The dog responds, as do other laboratory animals, to excessive doses of vitamin A.

2. This response is marked by loss of appetite, marked loss in weight, characteristic skeletal changes, hyperesthesia and exophthalmos.

3. Laboratory findings, with the exception of marked increases in the vitamin A content of the blood and a late drop in blood lipids (lipid-P and cholesterol), show no significant alterations.