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Journal of Nutrition Vol. 38 No. 2 June 1949, pp. 115-129
Copyright © 1949 by American Society for Nutrition
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Relation of Iodine to the Goitrogenic Properties of Soybeans1

Four Figures

A. W. Halverson, Marie Zepplin and E. B. Hart

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

1. The thyroid enlargement obtained with rations containing 10 and 30% of raw or heated soybeans was effectively prevented with 1 to 2 µg of iodine per rat per day. The iodine requirement of rats was slightly greater on soybean-containing rations than on the basal ration employed.
2. The reduced thyroid enlargement resulting from heat treatment indicates that the goitrogenic property of soybeans is partially heat labile.
3. Since small amounts of iodine effectively correct the mild goitrogenic property of soybeans, no harmful effects should result from the use of soybeans in practical rations.

1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. Supported in part by the Research Committee of the Graduate School from funds supplied by the Wisconsin Alumni Research Foundation. The authors wish to acknowledge the assistance of Mrs. Maria V. Adler in making many of the iodine determinations.

Manuscript received 16 February 1949.




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