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The Wrist Stiffness Syndrome in Guinea Pigs

Sedgwick E. Smith, M. A. Williams, A. C. Bauer and L. A. Maynard

School of Nutrition and Department of Animal Husbandry, Cornell University, Ithaca, New York

The occurrence of stiff wrist joints and tissue calcifications in guinea pigs fed certain diets has been confirmed. In our hands the diets originally used by the Oregon workers have proved unsatisfactory for this purpose, and our evidence does not support the view that the joint stiffness and the tissue calcifications are a part of the same syndrome. Evidence was not obtained that sugar cane juice, sugar cane bagasse, penicillin mold pad or ergostanyl acetate possess antistiffness activity.


Manuscript received 11 January 1949.





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Copyright © 1949 by American Society for Nutrition