Journal of Nutrition OpenSOurce Diets- www.ResearchDiets.com

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 36 No. 6 December 1948, pp. 761-772
Copyright © 1948 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nath, H.
Right arrow Articles by Hart, E. B.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Nath, H.
Right arrow Articles by Hart, E. B.

Studies of the Alleged Growth Promoting Property of Vaccenic Acid1

H. Nath, V. H. Barki, C. A. Elvehjem and E. B. Hart

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

1. No increase in the growth of young rats on diets containing either corn oil or olive oil resulted from supplementing the diets with vaccenic acid isolated from either butterfat or commercial hydrogenated cottonseed oil.
2. Replacing the sucrose by lactose or starch (rice) as the source of carbohydrate in the diets, or changing the levels of the water soluble vitamins, did not alter the results as far as the vaccenic acid supplementation was concerned.
3. Similar results were obtained when weanling rats from depleted mothers were used.
4. Supplementing a corn oil-lactose diet with either the cis or trans forms of synthetic vaccenic acid produced no growth stimulating effects.

1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. This work was supported in part by funds granted by the National Dairy Council, Chicago, on behalf of the American Dairy Association and by the Evaporated Milk Association, Chicago. We are indebted to Merck and Company, Inc., Rahway, New Jersey, for supplies of the synthetic B vitamins and a-tocopherol and to the Winthrop Chemical Company, Inc., New York, for crystalline vitamin D2.

Some of the preliminary work involved in this research was carried out in cooperation with Dr. R. P. Geyer, now at Harvard University.

The work with synthetic vaccenic acid was made possible by the generosity of Dr. F. M. Strong and associates, who successfully synthesized both the cis and trans forms.

Manuscript received 30 July 1948.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]