QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Maruyama, G. M. Articles by Phillips, P. H. Search for Related Content PubMed Articles by Maruyama, G. M. Articles by Phillips, P. H.

Reproduction and Lactation Studies with Rats Fed Natural and Purified Rations¹

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

1. Standardization of the experimental animal was found to be essential for reproduction and lactation studies.

2. Supplementing the basal "T" ration with 0.5% L(+)-lysine and 0.3% DL-methionine led to excellent reproduction and lactation in rats. The weight of the young weaned on this ration was less than that of young weaned on the casein-supplemented ration.

3. Supplemental folic acid appeared to be essential for normal reproduction and lactation in our female rats fed the corn-soybean-5% alfalfa ration or a purified ration.

4. The addition of 1% pancreatin or 5% corn steep liquor to the ration did not have any stimulative effect on reproduction or lactation, but 5% corn steep liquor did stimulate growth in the suckling young.

5. From these studies it is evident that in addition to other factors demonstrated to be helpful in reproduction and lactation — i.e., choline, B₆, inositol, and biotin — the amino acids L(+)-lysine and DL-methionine, and folic acid, are essential for good reproduction and lactation in female rats fed basal ration "T," which is essentially a corn-soybean oil meal-5% alfalfa ration.

^* Present address is Medical Associates, Dubuque, Iowa.

Manuscript received 30 April 1948.