Journal of Nutrition

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Journal of Nutrition Vol. 36 No. 3 September 1948, pp. 417-424
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Further Studies on the Relationship of Nicotinic Acid, Tryptophane and Protein in the Nutrition of the Pig1

R. W. Luecke, W. N. McMillen, F. Thorp, Jr. and Carolyn Tull

Departments of Agricultural Chemistry, Animal Husbandry and Animal Pathology, Michigan State College, East Lansing

Adequate amounts of DL-tryptophane as supplements to a low protein corn ration will prevent nicotinic acid deficiency in the pig. Supplementation of the same low protein ration with nicotinic acid seems to increase the utilization of dietary tryptophane.

No symptoms of nicotinic acid deficiency were produced on a corn ration containing 25% casein. Moreover, pigs fed this high protein ration grew very rapidly and required only 1.96 pounds of feed to produce 1 pound gain in body weight.

Mild symptoms of nicotinic acid deficiency were produced in pigs whose calculated average daily intake of nicotinic acid was 17.4 mg.

1 Published with the approval of the Director of the Michigan Agricultural Experiment Station as Journal Article no. 953 (n.s.). This work was supported in part by a grant from Merck and Company, Inc., Rahway, New Jersey. We are indebted to Merck and Company, Inc., and to the Dow Chemical Company, Midland, Michigan for the generous supplies of crystalline B vitamins and synthetic DL-tryptophane.

Manuscript received 1 May 1948.




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