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Growth and Reproduction of Swine on a Purified Diet^{1 ,2 ,3}

One Figure

Department of Agricultural Biochemistry, New Jersey Agricultural Experiment Station, Rutgers University, New Brunswick, New Jersey, and Merck Institute for Therapeutic Research, Rahway, New Jersey

Weanling pigs of 2 litters were maintained, for periods extending to 469 days, (a) on a purified diet supplemented with thiamine, riboflavin, niacin, pyridoxine, pantothenic acid, p-aminobenzoic acid, and choline; (b) on the purified diet with an additional daily supplement of 10 gm of dried liver; and (c) on an adequate commercial hog feed ("farm ration" control).

1. During the first 3 months after weaning, growth on the purified diet was at least equal to that on the "farm ration." Later, boars on the "farm ration" gained more weight than their litter mates on the purified diet.

2. Appearance and behavior of the animals maintained on the purified diet did not differ appreciably from that of the controls.

3. Feeding of the purified diet resulted in failure to reproduce.

4. The additional feeding of dried liver had no consistent effect on growth of the pigs maintained on the purified diet, and did not induce reproduction.

² This study was made possible by a grant from The Merck Institute for Therapeutic Research, Rahway, New Jersey.

³ Presented before the American Institute of Nutrition, Chicago, Ill., May 18–22, 1947.

⁴ Present address, Department of Agricultural Chemistry, University of New Hampshire, Durham, New Hampshire.

⁵ Present address, Department of Pharmacology, University of Illinois Medical School, Chicago, Illinois.

Manuscript received 2 August 1947.