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Journal of Nutrition Vol. 33 No. 5 May 1947, pp. 569-582
Copyright © 1947 by American Society for Nutrition
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The Effect of Fat Level of the Diet on General Nutrition

I. Growth, Reproduction and Physical Capacity of Rats Receiving Diets Containing Various Levels of Cottonseed Oil or Margarine Fat Ad Libitum1

Two Figures

Harry J. Deuel, Jr., Emily R. Meserve, Evelyn Straub, Cornelia Hendrick and Bradley T. Scheer

Department of Biochemistry and Nutrition, University of Southern California School of Medicine, Los Angeles

Ad libitum feeding to rats of diets varying in fat content from 5 to 50% (10 to 70% of total cal.) results in better growth, greater physical capacity, and better reproductive and lactation performance in rats than does feeding of diets containing minimal amounts of fat. The difference is not influenced by presence of methyl linolate in the fat-free diet. Optimum growth was observed on diets containing 20–40% fat. The most pronounced differences were observed in males. The effects are in part, but not entirely, attributable to greater caloric intake on the diets containing fat.

1 This work was carried out under a research grant from The Best Foods, Inc. The authors wish to acknowledge the helpful advice of Professor Anton J. Carlson of the University of Chicago, of Professor Arthur W. Thomas of Columbia University and of Dr. H. W. Vahlteich of The Best Foods, Inc., during the course of the experiments.

We are indebted to Merck and Co., Rahway, N. J., for the synthetic B vitamins; to the Winthrop Chemical Co., Albany, N. Y., for the crystalline vitamin D2 and to Lederle Laboratories, Inc., for the folic acid.

Manuscript received 27 November 1946.




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