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Journal of Nutrition Vol. 33 No. 5 May 1947, pp. 505-509
Copyright © 1947 by American Society for Nutrition
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The Renal Threshold for Ascorbic Acid

A Modified Method for its Estimation with Results for Twelve Adult Subjects1

Ann Moore Klosterman, J. Estelle Haines, Hazel M. Hauck and Alice B. Kline

New York State College of Home Economics, and School of Nutrition, Cornell University, Ithaca, New York

A modified method for estimating the renal threshold for ascorbic acid based on the comparison of means and standard deviations for urinary excretions at various plasma ascorbic acid levels is presented. This method is simpler and appears to have a wider usefulness than that previously reported from this laboratory.

The renal thresholds for 12 normal adults, as estimated by this method, were between 1.0 and 1.3 mg %.

Further evidence is presented that the renal threshold for ascorbic acid is relatively stable from year to year.

1 Some of the data in this paper are taken from theses presented to the faculty of the Graduate School of Cornell University in fulfillment of the requirement for the M.S. degree, by Ann C. Moore, June 1944, and J. Estelle Haines, February 1946. Further details will be found in the theses.

Manuscript received 27 November 1946.




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