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The Effect of Crude Lecithin on the Coefficient of Digestibility and the Rate of Absorption of Fat^{1 ,2}

Department of Biochemistry and Nutrition, University of Southern California School of Medicine, Los Angeles

The addition of lecithin to cottonseed oil or to a hydrogenated cottonseed oil markedly lowers the susceptibility to diarrhea caused by a large dose of these fats to rats.

Fats containing one-sixth or one-fifth crude lecithin are absorbed more rapidly than a similar fat without any added phosphatide.

It was found that hydrogenated cottonseed oil melting at 63°C. had a digestibility of 24 in the rat; that melting at 54°C. was digested to the extent of 69% while that with a melting point of 46°C. had a digestibility coefficient of 84. These were increased by the addition of lecithin to 44, 83 and 88%, respectively.

A considerably larger portion of the lipid in all cases was excreted as soaps than as neutral fat plus fatty acids.

² Aided by a grant from the American Lecithin Co.

Manuscript received 24 September 1946.