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Observations on Pellagra in American Prisoners of War in the Philippines

University Hospital, Ann Arbor, Michigan

1. Pellagra was observed in American troops living for 3 years on a deficient diet in Japanese Prison Camps in the Philippine Islands.

2. Men developed pellagra while on a diet low in calories, high in carbohydrates and lacking in animal proteins, fresh fruits, and vegetables.

3. Pellagra appeared in epidemic proportions after 6 months on a deficient diet.

4. The signs and symptoms that were observed are described. The clear separation of certain dermal and neurological lesions according to specific vitamin lack was difficult.

5. Processed foods, a crude yeast culture, and pure vitamin preparations were effective in controlling pellagra. Pure vitamin preparations were more effective when the diet was more adequate.

6. The daily multivitamins utilized during 1944 reduced the incidence of the severe pellagra seen in 1942 and 1943.

Manuscript received 15 July 1946.