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Vitamin Bc and its Relation to ß-Pyracin Lactone in the Metabolism of the Chick

C. J. Campbell, R. A. Brown, O. D. Bird and A. D. Emmett

The Research Laboratories, Parke, Davis and Company, Detroit, Michigan

conclusions. Based upon the experimental conditions as carried out in these laboratories the following conclusions are warranted.

1. Crystalline vitamin Be is required by the chick for normal growth, feathering and hemopoiesis. This confirms our previous findings.
2. In the presence of a sub-optimal amount of crystalline vitamin Bc, ß-pyracinlactone has no supplemental effect on growth, feathering and hemopoiesis of the chick, even in the presence of succinylsulfathiazole (with or without PABA). This suggests that L. casei factor from a fermentation residue is not the same as vitamin Bc.


Manuscript received 13 May 1946.





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