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Journal of Nutrition Vol. 32 No. 1 July 1946, pp. 93-99
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The Effect of Liver Extracts on the Utilization of Casein for Growth1

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D. K. Bosshardt, Mary M. Ayres, Laura C. Ydse and R. H. Barnes

The Department of Biochemistry, Medical Research Division, Sharp and Dohme, Inc., Glenolden, Pennsylvania

Two liver fractions, Wilson's 1:20 powder and a butyl alcohol extract of the 1:20 powder, have been shown to contain a factor, or factors, that enhances the growth rate and the growth utilization of dietary protein in mice. The effect on protein utilization is demonstrated most clearly when the maximal ratios of body protein gained to protein absorbed are compared.

1 A preliminary report of this investigation was presented before the Philadelphia section of the American Chemical Society June 13, 1945.

Manuscript received 30 January 1946.




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