Journal of Nutrition

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 31 No. 4 April 1946, pp. 497-507
Copyright © 1946 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nelson, M. M.
Right arrow Articles by Evans, H. M.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Nelson, M. M.
Right arrow Articles by Evans, H. M.

Pantothenic Acid Deficiency and Reproduction in the Rat1

Marjorie M. Nelson and Herbert M. Evans

Institute of Experimental Biology, University of California, Berkeley

Reproduction has been studied in normal adult female rats placed on purified diets deficient in pantothenic acid before or during the gestation period.

Pantothenic acid deficiency instituted on the thirteenth day of gestation did not interfere with the reproductive function. Pantothenic acid deficiency instituted 16–23 days before mating or as late as the day of mating always resulted in failure of implantation, resorption, or defective litters.

The normality of reproduction in pantothenic acid-fed controls restricted in calories eliminated the factors of inanition and of other specific dietary deficiencies as causes for these marked upsets in reproduction.

1 Aided by grants from the Board of Research and from the Department of Agriculture of the University of California, and the Rockefeller Foundation, New York City. The following materials were generously contributed: crystalline B vitamins from Merck and Company, Inc., Rahway, New Jersey; synthetic alpha-tocopherol from Hoffmann-LaRoche Company, Nutley, New Jersey.

Manuscript received 8 November 1945.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]