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Nicotinic Acid Deficiency in Turkey Poults and the Occurrence of Perosis¹

One Figure

Department of Poultry Husbandry, University of Maryland, College Park, Maryland

Turkey poults, when fed a highly purified diet containing all necessary nutrients except nicotinic acid, grew poorly and developed certain deficiency symptoms such as inflammation of the mouth, diarrhea, low feed consumption, poor efficiency of feed utilization, poor feathering, and perosis. The perosis in the deficient birds occurred in spite of ample manganese, choline, and biotin in the diet. All symptoms were prevented by the addition of 3 to 5 mg. of nicotinic acid per 100 gm. of ration. Higher levels of nicotinic acid, however, may be needed for optimum growth.

The author is indebted to Merck and Co., Inc., Rahway, N. J., for the crystalline vitamins; Wilson and Co., Inc., Chicago, Ill., for gelatin; The Wilson Laboratories, Chicago, Ill., for Liver Fraction L; Allied Mills. Inc., Portsmouth, Va., for soybean oil; Abbott Laboratories, North Chicago, Ill., for Haliver oil; E. I. du Pont de Nemours and Co., New Brunswick, N. J., for irradiated 7-dehydro-cholesterol; to Mr. Stanley Weaver and Mr. Carl Spitzer for assistance in various phases of the work, and to Dr. M. A. Jull for valuable suggestions.

Manuscript received 3 August 1945.