Journal of Nutrition

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Journal of Nutrition Vol. 31 No. 1 January 1946, pp. 23-33
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The Use of Mice for the Measurement of the Growth Promoting Quality of Proteins

Five Figures

D. K. Bosshardt, Laura C. Ydse, Mary M. Ayres and R. H. Barnes

Department of Biochemistry. Medical Research Division, Sharp and Dohme, Inc., Glenolden, Pennsylvania

The method of Osborne, Mendel and Ferry for the measurement of protein efficiency ratios (grams gain in body weight per gram of protein consumed) has been adapted for use with mice.

The importance of establishing standardized conditions with regard to the pre-test treatment of the test animals, the duration of the test period, and the level of test protein in the diet has been demonstrated.

The advantages of the use of the mouse as compared with the rat are: smaller animal size, lower food consumption, and shorter test periods.


Manuscript received 9 August 1945.


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D. Vedenov and G. M. Pesti
A comparison of methods of fitting several models to nutritional response data
J Anim Sci, February 1, 2008; 86(2): 500 - 507.
[Abstract] [Full Text] [PDF]




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