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Journal of Nutrition Vol. 30 No. 2 August 1945, pp. 143-146
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Experimental Rickets in the Hamster1

James H. Jones

Department of Physiological Chemistry, University of Pennsylvania, School of Medicine, Philadelphia

On a diet containing approximately 0.4% calcium and 0.02% phosphorus with no added vitamin D hamsters developed all of the symptoms characteristic of experimental rickets observed in the rat on similar diets. Calcification was as rapid on a diet containing optimal amounts of calcium and phosphorus and no vitamin D as on the same diet to which the vitamin had been added.

Typical rickets can be produced in the hamster, but as with the rat the diet must be low in phosphorus as well as deficient in vitamin D.

1 The data included in this paper were presented in abstract form in Federation Proceedings, 1945, vol. 4, p. 156.

Manuscript received 8 May 1945.




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