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Observations on Riboflavin Excretion by the Adult Male¹

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Department of Medicine, University of Wisconsin, Madison

Studies made on a group of adult male prisoners showed that after ingestion of riboflavin supplements in the form of tablets or foods rich in vitamins there was an increase of riboflavin excreted in the urine. The retention of riboflavin from such supplements varied from 17 to 80% with no apparent reason for the wide fluctuations. No physical findings were seen to indicate riboflavin deficiency in those men who for 2 years or more must have been eatting not much over 0.5 mg. daily, and who were excreting 0.05 to 0.12 mg. riboflavin in the 24-hour urine. It is felt that satisfactory criteria of need for riboflavin by the human adult are still lacking.

Manuscript received 14 September 1944.