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Research Laboratories, Winthrop Chemical Co., Inc., Rensselaer, New York
A severe anemia develops in pigeons maintained on a purified ration containing thiamine, riboflavin, pyridoxine, nicotinic acid, and calcium pantothenate, but lacking other members of the vitamin B-complex. The hemoglobin levels may be restored to normal by administering extracts of yeast, of liver, and of rice bran. The anti-anemic agent in a solution of liver extract remains in the filtrate upon treatment with fuller's earth at pH 4.0.
Evidence is also presented to demonstrate that a second or weight-restoration factor is required by the pigeon.
Manuscript received 16 June 1944.