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Journal of Nutrition Vol. 28 No. 2 August 1944, pp. 93-100
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Further Studies on the Vitamin C Metabolism of Preschool Children

Frieda L. Meyer1 and Milicent L. Hathaway

New York State College of Home Economics, Cornell University, Ithaca

The ascorbic acid metabolism has been studied in eight preschool children. The basal diet containing 23 to 25 mg. ascorbic acid was supplemented with 100 mg. ascorbic acid, 3.38 gm. potassium citrate, or equivalent amounts of orange juice as indicated. The results were as follows:

1. A daily intake of 23 to 25 mg. of ascorbic acid was not sufficient to maintain tissue saturation in the eight children.
2. On the addition of 3.38 gm. potassium citrate to the diet "utilization" of ascorbic acid was increased in five of the eight children at both levels of ascorbic acid intake (25 and 125 mg.), and in two others at the higher level of ascorbic acid intake.
3. On the substitution of orange juice for crystalline ascorbic acid and potassium citrate, the "utilization" of ascorbic acid was significantly increased in the four children studied.
4. The "utilization" of ascorbic acid was not directly related to the urinary pH.


1 Now at Wayne University Medical College, Department of Surgery, Detroit, Mich.

Manuscript received 24 September 1943.





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