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Journal of Nutrition Vol. 27 No. 1 January 1944, pp. 1-9
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The Nutrition of the Cotton Rat (Sigmondon Hispidus Hispidus)1

One Figure

J. M. McIntire, B. S. Schweigert and C. A. Elvehjem

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

Cotton rats require thiamine, riboflavin, pantothenic acid, pyridoxine and choline in approximately the same quantities as the white rat; in addition they require nicotinic acid and inositol. Rats on a completely synthetic diet grow at a rate of only 5.6 gm. per week.

Additional growth promoting substances are present in 1:20 liver extract. This is indicated by the increase in growth rate to 8.6 gm. per week when 2% liver extract is added to the ration.

1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. This work was supported in part by a grant from the National Live Stock and Meat Board made through the National Research Council. We are indebted to Merck and Company, Rahway, New Jersey, for supplies of thiamine, nicotinic acid, riboflavin and pyridoxine; to Abbott Laboratories, North Chicago, Illinois, for the haliver oil; and to Wilson and Company, Chicago, Illinois, for the liver extracts.

Manuscript received 2 August 1943.




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