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Department of Chemistry, Columbia University, New York City
Offspring of rat families whose diets, otherwise similar, contained respectively 3, 6, and 12 I.U. of vitamin A per gram of air-dry food, were killed at ages of 30 and 60 days and the vitamin A values of their liver and muscle tissues determined. Whether compared at the age of 30 or 60 days the vitamin A in the liver was found to have been decidedly influenced by the level of nutritional intake of this vitamin. The skeletal muscles of the same animals showed differences in the same direction, but so small as to be of doubtful statistical significance. Storage of vitamin A in the body, as reflected by the concentration in the liver, was found to have continued in the second age period studied when the level of nutritional intake of the vitamin was high but not when it was near the minimal-adequate level.