Journal of Nutrition

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Journal of Nutrition Vol. 25 No. 4 April 1943, pp. 379-387
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Fat Excretion by Normal Children1

Harold H. Williams, Elizabeth N. Endicott, Marion L. Shepherd, Harry Galbraith and Icie G. Macy

Research Laboratory of the Children's Fund of Michigan, Detroit, Michigan

The fat excretion of nineteen healthy children, ages 4 to 12 years, was investigated over 513 5-day periods while they were ingesting diets of high nutritive quality. Fat intakes ranged from 62 to 113 gm. per day and the utilization varied from 96 to 98%. An average daily excretion of 2.3 gm. of lipids, which represented an average of 13% of the fecal dry weight, was observed.

Feces dried from frozen state under vacuum were used in determinations of the fecal lipid partition for eight children over eleven consecutive 5-day periods. Four children received 83 gm. (3.1 gm./kg.) of fat per day and the other four, 113 gm. (3.2 gm./kg.). Excretion of free fatty acid, neutral fat and unsaponifiable material was approximately equal for all the subjects but the soap excretion was significantly higher for the children with the larger fat intakes, 1.93 ± 0.36 gm. (54.2 mg./kg.) as compared with 1.40 ± 0.55 mg. (52.1 mg./kg.). For all the children soaps comprised approximately 50% of the total fecal fat, unsaponifiable fat represented approximately 30%, and the remainder was almost equally divided between free fatty acid and neutral fat.


1 Preliminary reports of part of this work were given before the 100th meeting of the American Chemical Society, Detroit, Michigan, September 9–13, 1940, and before the American Society of Biological Chemists at the meeting of the Federation of American Societies for Experimental Biology, Toronto, Canada, April 26–29, 1939.

Manuscript received 30 October 1942.





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