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Journal of Nutrition Vol. 24 No. 5 November 1942, pp. 449-460
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The Riboflavin Requirement of the Dog1

Two Figures

R. L. Potter2, A. E. Axelrod and C. A. Elvehjem

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

1. Under the experimental conditions described, the riboflavin requirement for the growing dog lies between 60 and 100 µg. per kilogram of body weight per day.
2. The isocaloric substitution of lard for sucrose does not increase the riboflavin requirement of the growing dog.
3. The following symptoms are associated with riboflavin deficiency: (1) fatty liver, (2) dermatitis, (3) muscular weakness of the hind quarters, (4) conjunctivitis, vascularization of the cornea, corneal opacities, and (5) tachycardia.


1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. This study was aided by grants from the Rockefeller Foundation and the Works Progress Administration.

2 Commercial Solvents Corporation Fellow.

Manuscript received 24 June 1942.





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