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Journal of Nutrition Vol. 24 No. 3 September 1942, pp. 295-306
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The Effect of the Level of Protein Intake upon the Urinary Excretion of Riboflavin and Nicotinic Acid in Dogs and Rats1

Two Figures

Herbert P. Sarett2, J. Raymond Klein and William A. Perlzweig

Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina

The urinary excretions of nicotinic acid by dogs and of riboflavin by both dogs and rats bear an inverse relationship to the level of protein intake.

Riboflavin and nicotinic acid are inferred to be concerned in protein anabolism.

1 A preliminary report was given before the American Society of Biological Chemists, April, 1942 (Federation Proceedings I, 132, 1942). Aided in part by the John and Mary R. Markle Foundation, the International Health Division of the Rockefeller Foundation and the Duke University Research Council.

2 Upjohn Fellow in Biochemistry.

Manuscript received 8 June 1942.




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