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Journal of Nutrition Vol. 24 No. 1 July 1942, pp. 65-72
Copyright © 1942 by American Society for Nutrition
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A Liver Concentrate as a Source of Unrecognized Vitamins Required by the Chick1

One Figure

Luther R. Richardson, Albert G. Hogan and Richard J. Karrasch

Department of Agricultural Chemistry, College of Agriculture, University of Missouri, Columbia

1. When chicks receive a ration that contains no vitamins except those now recognized as such, they grow slowly and develop perosis.
2. A water extract of beef liver contains all unrecognized vitamins required by the chick.
3. The unrecognized vitamins required by chicks are adsorbed from a water extract of liver by fuller's earth at a pH of 1.0. The activity is readily eluted by 0.2 N ammonia. During the adsorption procedure approximately one-third of the total activity is lost.
4. A simplified diet has been prepared that is adequate for the growth of chicks and does not contain over 1% of crude vitamin carriers.

1 Contribution from the Missouri Agricultural Experiment Station Journal Series No. 808.

Manuscript received 16 February 1942.




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